Central-Variant Posterior Reversible Encephalopathy due to Sulfasalazine: A Case Report

نویسندگان

  • Levent Ocek
  • Ufuk Sener
  • Burcu S. Demirtas
  • Metin M. Ozcelik
  • Ozgur Oztekin
  • Yasar Zorlu
چکیده

OBJECTIVE To report a rare case with central-variant posterior reversible encephalopathy syndrome due to sulfasalazine. CLINICAL PRESENTATION AND INTERVENTION A 55-year-old female patient presented with seizure and acute-onset hemiparesia. Thirty days earlier, treatment with sulfasalazine was commenced in response to a diagnosis of psoriatic arthritis. Laboratory examinations were normal. Brain magnetic resonance imaging showed symmetric edema within basal ganglia and thalami with sparing of the cerebral cortices. After stopping the treatment of sulfasalazine, clinical and radiological findings regressed dramatically. CONCLUSION This was a case of central-variant posterior reversible encephalopathy syndrome due to sulfasalazine, and atypical imaging findings should be kept in mind for early diagnosis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Unexpected Maternal Convulsion: An Idiopathic Case of Posterior Reversible Encephalopathy Syndrome after Delivery

Posterior reversible encephalopathy syndrome (PRES) is associated with various clinical manifestations such as headache, blurred vision, confusion and tonic-clonic convulsion. Some of the predisposing factors for PRES include hypertensive encephalopathy, preeclampsia and eclampsia, lupus erythematosus, thrombotic thrombocytopenic purpura and long-term use of immunosuppressive drugs. This condit...

متن کامل

Posterior reversible Leukoencephalopathy following thrombotic thrombocytopenic purpura at postpartum period: case report

Background: Posterior reversible leukoencephalopathy syndrome (PRLS) is a clinical and radiological syndrome of heterogeneous etiologies that are grouped because of the similar findings on neuroimaging studies which may occur at any age. The pathogenesis of RPLS remains unclear, but it appears to be related to disordered cerebral autoregulation and endothelial dysfunction. The syndrome is more ...

متن کامل

Posterior Reversible Encephalopathy Syndrome Mimicking Brainstem Infarction: A Dilemma.

PURPOSE We had recently reported one case at American Journal of Emergency Medicine about centralvariant posterior reversible encephalopathy syndrome (PRES) in an 84-year-old woman with an initial misdiagnosis as central pontine myelinolysis (CPM). Here, we introduce another case of centralvariant PRES in a 49-year-old man mimicking as acute brainstem infarction in the cranial computed tomograp...

متن کامل

JOURNAL OF MEDICAL CASE REPORTS Posterior reversible encephalopathy syndrome in a child with cyclical vomiting and hypertension: a case report

Introduction: Posterior reversible encephalopathy syndrome is characterized by headache, nausea and vomiting, seizures and visual disturbances. It has certain characteristic radiological features, which allow diagnosis in the appropriate clinical setting and enable appropriate clinical therapy to be instituted. Case presentation: A 10-year-old Caucasian girl who was hospitalized due to recurren...

متن کامل

Posterior reversible encephalopathy syndrome in a child with cyclical vomiting and hypertension: a case report

INTRODUCTION Posterior reversible encephalopathy syndrome is characterized by headache, nausea and vomiting, seizures and visual disturbances. It has certain characteristic radiological features, which allow diagnosis in the appropriate clinical setting and enable appropriate clinical therapy to be instituted. CASE PRESENTATION A 10-year-old Caucasian girl who was hospitalized due to recurren...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 24  شماره 

صفحات  -

تاریخ انتشار 2015